Mubarak who was born in 1928 succeeded his predecessor Anwar Sadat following his assassination in 1981 and ruled Egypt until 2011 when a wave of anti-government protests culminated in his ouster.
Months earlier protests in neighbouring Tunisia had ousted his counterpart Abedine Ben Ali.
He died at a military hospital, a local newspaper reported.
The former air force officer who was a key figure of the 1973 Arab-Israeli conflict has been recovering from surgery which was conducted on him in January.
He was put under intensive care over the weekend, a family member said on Saturday.
Mubarak was found guilty in relation to the killing of protesters during the 2011 so-called Arab Spring uprising in Egypt which eventually led to his downfall.
He was freed in 2017 after a court overturned the conviction.
The government of Abdel Fattah al-Sisi has not yet announced the date for his funeral.