Provincial health spokesperson Azarias Gimo told APA that the casualties were among 184,778 malaria cases recorded in the province since January.
This is almost the same number of deaths recorded during the same period in 2017 when the disease had by this time killed 46 people out of 154,518 diagnosed cases.
"In relation to malaria, there was an increase of 20 percent compared to the first five weeks of 2017, which obviously is of great concern," Gimo said.
He said the worst affected districts were Nampula, Ilha de Moçambique, Murrupula, Mossuril, Muecate, Lalaua and Monapo.
Provincial health officials have distributed more than 3.5 million mosquito nets since 2016 under the government’s malaria prevention and control programme.
Malaria is among the leading causes of deaths in the south-eastern African country of 28.8 million people together HIV/AIDS and tuberculosis.