According to latest statistics, South Africa had recorded more than 264,000 cases of COVID-19 and nearly 4,000 deaths as of Sunday morning.
This was almost 10,000 more cases that 11th-placed Iran, which had registered 255,117 cases by Sunday morning.
According to Health Minister Zweli Mkhize, there were nearly 13,500 new cases recorded in South Africa between Friday and Saturday.
The United States continued to lead the global roll call for COVID-19 cases, with nearly 3,355,780 confirmed cases or 26 percent of the 12,849,435 cumulative cases recorded by all the countries in the world.
There have been more than 137,400 deaths in the US alone since the pandemic broke out early this year.
Brazil remains in second place with over 1,840,800 cases, followed by India, Russia, Peru, Chile, Spain, Mexico and the United Kingdom.
In terms of the African Top 5 ranking, Egypt has the second highest number of cases at 81,158 cases as of Sunday morning, followed by Nigeria (31,987), Ghana (24,248), and Algeria (18,712)