The deceased in the crash were burned beyond recognition after the vehicle they were trapped in caught fire.
There were six survivors, who had been taken to nearby health facilities.
The Kintampo Divisional Crime Officer, DSP Kwabena Gbagbo, told Citi Fm that the crash occurred at 3 am on Monday.
One of the buses involved in the crash was travelling from Bawku to Techiman when the crash occurred near an area called Dawadawa No 2.
It had 11 passengers on board, while the other, vehicle a Sprinter bus had 23 passengers.
“All the passengers in the Sprinter bus were burnt beyond recognition. Out of the 11 passengers on board the other bus, only six people survived. Five, together with the driver, also got burnt beyond recognition,” DSP Gbagbo said.
This is the second time this year Ghana has recorded a gruesome accident. The first crash was between an Intercity bus that collided head-on with another bus at Dompoase near Elmina in the Central Region, resulting in 35 deaths early this year.